Near infrared spectroscopy, or NIRS, is a scanning technique that uses light of the near infrared (NIR) spectrum for detection of specific molecules. The method is used in the pharmaceutical, medical, diagnostic, food and agrochemical industry.

Since 1977, the year that the brain tissue transparency to NIR light was discovered, many developments have occurred, in order to make the state-of-the-art NIRS as a non-invasive tissue-illumination technique. The first alteration in the NIRS principle was made in the early 1980s, when instead of illuminating the sample by transmission of light through the sample (transillumination), the technique based on reflectance of light was used.

These developments of NIRS, however, were insufficient to make NIRS an accurate detection method, The research question of this project is "Development of novel methods to improve the accuracy of detection and localization of NIRS"

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